- Chris Pine James T. Kirkinä
- Zachary Quinto Spockina
- Karl Urban hahmona Leonard McCoy
- Zoe Saldana hahmona Uhura
- John Cho Hikaru Suluna
- Anton Yelchin Pavel Chekovina
- Simon Pegg Montgomery Scottina
- Bruce Greenwood Christopher Pikenä
- Winona Ryder Amanda Graysonina
- Eric Bana Nerona