* The X-Files (1994-2002) nimellä Det. Dana Scully
* The Lone Gunmen (2001-2002) Det. Dana Scully
* Millennium (1996-1999) nimellä Det. Dana Scully
* Fringe (2008-2013) Det. Olivia Dunham
* Otettu (2002) hahmona Kate Ryan
* The Practice (2000-2001) hahmona Kate Ryan
* NYPD Blue (1993-2005) Det. Jane Timoney
* CSI:Miami (2002-2012) Det. Calleigh Duquesne
* Without a Trace (2002-2009) Det. Samantha Spade
* Numb3rs (2005-2010) hahmona Dr. Charlie Eppes
* Monk (2002-2009) hahmona Sharona Fleming
* Psych (2006-2014) Det. Juliet O'Hara
* Burn Notice (2007-2013) hahmona Sam Axe
* Leverage (2008-2012) hahmona Sophie Devereaux
* White Collar (2009-2014) hahmona Neal Caffrey
* Covert Affairs (2010-2014) hahmona Annie Walker
* The Americans (2013-2018) hahmona Elizabeth Jennings
* The Blacklist (2013-2019) hahmona Elizabeth Keen
* The Catch (2016-2017) hahmona Alice Vaughan
* Quantico (2015-2018) Alex Parrishina
Elokuva
* The X-Files:Fight the Future (1998) hahmona Det. Dana Scully
* The X-Files:I Want to Believe (2008) hahmona Det. Dana Scully
* Alien:Resurrection (1997) hahmona Lt. Ellen Ripley
* Itsenäisyyspäivä (1996) kapteenina Steven Hiller
* The Net (1995) hahmona Angela Bennett
* A Time to Kill (1996) hahmona Ellen Roark
* The Negotiator (1998) hahmona Christy Sabich
* Deep Blue Sea (1999) hahmona Dr. Susan McAlester
* Vertical Limit (2000) hahmona Annie Garrett
* Frequency (2000) hahmona Julia Sullivan
* The Gift (2000) hahmona Katie Holmes
* The Bourne Identity (2002) hahmona Marie Kreutz
* Kaikkien pelkojen summa (2002) hahmona tohtori Catherine Muller
* The Bourne Supremacy (2004) hahmona Marie Kreutz
* The Bourne Ultimatum (2007) hahmona Marie Kreutz
* Evan Almighty (2007) hahmona Joan Baxter
* The Invasion (2007) hahmona Carol Bennell
* The Ruma totuus (2009) hahmona Abby Richter
* Love Happens (2009) hahmona Dr. Eloise Chance
* The Conspirator (2010) hahmona Mary Surratt
* The Adjustment Bureau (2011) hahmona Elise Sellas
* Margin Call (2011) hahmona Sarah Robertson
* Tower Heist (2011) FBI-agenttina Claire Denhamina
* Zero Dark Thirty (2012) hahmona Maya
* The Fifth Estate (2013) hahmona Rebecca MacKinnon
* Kapteeni Phillips (2013) hahmona Irene Phillips
* Big Eyes (2014) hahmona Margaret Keane
* Foxcatcher (2014) hahmona Nancy Schultz
* Joy (2015) hahmona Trudy Campanello
* Collateral Beauty (2016) hahmona Claire Wilson
* Hidden Figures (2016) hahmona Vivian Mitchell
* The Shape of Water (2017) hahmona Zelda Fuller
* Lady Bird (2017) hahmona Marion McPherson
* Three Billboards Outside Ebbing, Missouri (2017) hahmona Mildred Hayes
* A Quiet Place (2018) hahmona Evelyn Abbott
* A Quiet Place Part II (2020) hahmona Evelyn Abbott
* Älä katso ylös (2021) hahmona Jane Orlean